Our Products Improve Livestock Farming and Aquaculture

Gut Health

Proteon’s bacteriophage products have the potential of modulating the gut microbiota and immune functions. Phages target and inactivate specific bacterial pathogens what creates space for proliferation of the beneficial microflora, hence prevents dysbiosis, improves balance and overall gut health.

Definition

Gut Health

The gut is the largest organ of the body, which makes it also the first line of defence against pathogenic organisms. Animals’ gut health has significant implications for health, wellness, productivity, food safety and environment. The gastrointestinal tract requires proper gut health to function effectively as it conditions the digestive, absorptive, metabolic, immunological and endocrine functions.

Impacts

Gut health problems & productivity threats

The integrity of the delicate equilibrium between the host, intestinal microbiota, intestinal environment, and dietary components is crucial to gut health. This balance can be influenced by gut inadequate development, infections, feed quality, temperature, ventilation, brooding conditions, water quality, and other environmental factors.

The majority of gut health disorders stay undetected since they are rarely reflected in clinical symptoms, however even subclinical levels of pathogenic bacteria can disturb the gut microbiome balance and weaken the animal’s health. As a disease develops and progresses, it can become all-consuming and uncontrollable, resulting in low productivity and high mortality rates.

Impact on Gut Microbiome: Antibiotics reduce the healthy diversity

Importance of Gut Health & Microbiome

A healthy gastrointestinal systems in livestock animals can help achieving optimal production of meat or eggs. Intestine is responsible for digestion and absorption, but it also plays a vital role in regulating immunological responses. Microbiome is one of the most important elements of the intestine.

Microbiota is defined as a community of microorganisms mostly comprised of bacteria, viruses and fungi. Maintaining the appropriate diversity and balance of the gut microbiota is vital to its proper functioning and protection of the organism against illnesses. Any alterations of the natural microflora balance, for instance by antibiotic application, disrupts the integrity of the intestinal walls and as a consequence can result in the development of acute disease symptoms. When gut health is disrupted, it also compromises nutrient absorption and digestive system. This has an immense impact on animal health, feed consumption and conversion that contribute to economic losses.

How Proteon can help you contribute to solving the challenges

The influence of bacteriophages on Gut Health

Phages acts opposite to antibiotics, which have wide spectrum of action and kill not only bacterial pathogens but also beneficial gut microflora. Bacteriophages have the potential of modulating the gut microbiota and immune functions through acting only against their targeted bacteria. The gut microbiota consists of diverse range of bacteria, fungi, protozoa and viruses, where pathogenic bacteria can continuously replicate and damage the gut. Phages target and inactivate specific bacterial pathogens what creates space for proliferation of the beneficial microflora, hence prevents dysbiosis, improves balance and overall gut health. This translates into better performance and reliable results.

Where Do We Operate

Join Hands With Us! Find Us Here
Headquarters & Legal Address:
UI. Tylna 3a 90-364 Lodz, Poland
Commercial Office Address
LIM Center 18th Floor AI. Jerfozolimskie 65/79, 00-697 Warsaw, poland
Asia Office Address
VETPHAGE PHARMACEUTICALS PRIVATE LIMITED A-310, Western Edge II, Behind Metro Mall,Western Express Highway, Borivali East, Mumbai, Maharashtra, India. 400 066

Learn more on our channels:

Sources

‘Gut health’: a new objective in medicine?, National Library of Medicine: Available Here
Microbiome definition re-visited: old concepts and new challenges, National Library of Medicine: Available Here
What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases, National Library of Medicine: Available Here
Proteon Pharmaceuticals Internal Researches